HOME THERAPY AREAS Economic justification of cell culture-based influenza vaccines in children and adults: a review of cost-effectiveness analyses 2 October 2025 Vaccines Vaccines Seasonal influenza has a significant health and economic impact on children and adults. This review [1] summarizes cost-effectiveness analyses regarding the use of cell-culture-based influenza vaccines in children and adults under 65 years of age. Among others, 9 cost-effectiveness analyses in 8 countries compared the cell-culture-based quadrivalent influenza vaccine Flucelvax with egg-based vaccines. Explore the cost-effectiveness of cell-culture-based quadrivalent influenza vaccine Flucelvax vs. egg-based vaccines View PDF > German View PDF > French View PDF > Italian 1. Fisman D, Giglio N, Levin MJ, Nguyen VH, Pelton SI, Postma M, Ruiz-Aragón J, Urueña A, Mould-Quevedo JF. The economic rationale for cell-based influenza vaccines in children and adults: A review of cost-effectiveness analyses. Hum Vaccin Immunother. 2024 Dec 31;20(1):2351675.