HOME THERAPY AREAS Guiding you through Glomerular Disease: an interactive approach to learning more on IgAN and FSGS 11 October 2022 Nephrology and Rare Diseases Glomerular Disease CSL Vifor is dedicated to supporting patients with Glomerular Disease. Glomerular Diseases such as IgA Nephropathy (IgAN) and Focal Segmental Glomerulosclerosis (FSGS), account for 25% of the cases of CKD worldwide. FSGS is a histological pattern of glomerular damage, occurring as a consequence of varying insults to several renal cells, including podocytes, and is a leading glomerular cause of kidney failure that profoundly impacts patient quality of life. IgAN is an immune complex-mediated glomerulonephritis caused by the deposition of IgA1 in the glomerular mesangium and is the most prevalent primary glomerulonephritis worldwide, often progressive and, if not controlled, is a major cause of kidney failure. Through our interactive tool, learn more on the epidemiology, burden, pathogenesis, prognostic factors, etiology, treatment goals and unmet needs of IgAN and FSGS.